Epigenetic gene regulation
2023
Hyeonju Woo, Junsoo Oh, Jung-Shin Lee, TaeSoo Kim*, N-terminal actylation of Set1-COMPASS by NatA fine-tunes H3K4 methylation patterns. In preparation
2021
Bo Bae Lee, Hyeonju Woo, Min Kyung Lee, SeoJung Youn, Sumin Lee, Jae-Seok Roe, Soo Young Lee, TaeSoo Kim*
Core promoter activity contributes to chromatin-based regulation of internal cryptic promoters
Nucleic Acids Research, 49(14), 8097–8109 (2021)
Jae Woo Shin, Jihyun Kim, Seokjin Ham, Sun Mi Choi, Chang-Hoon Lee, Jung Chan Lee, Ji Hyung Kim, Sang-Heon Cho, Hye Ryun Kang, You-Me Kim, Doo Hyun Chung, Yeonseok Chung, Yoe-Sik Bae, Yong-Soo Bae, Tae-Young Roh, TaeSoo Kim, Hye YoungKim. A unique population of neutrophils generated by air pollutant-induced lung damage exacerbates airway inflammation. Journal of Allergy and Clinical Immunology (2021)
Ho-Soo Lee, Sunwoo Min, Ye-Eun Jung, Sunyoung Chae, June Heo, Jae-Ho Lee, TaeSoo Kim, Ho-Chul Kang, Makoto Nakanish, Sun-Shin Cha & Hyeseong Cho. Spatiotemporal coordination of the RSF1-PLK1-Aurora B cascade establishes mitotic signaling platforms. Nature Communications (2021)
Kim M, Lin J, Huh JE, Park JH, Go M, Lee H, Hwang D, Kim HS, Kim T, Lee D, Lee SY. Tetraspanin 7 regulates osteoclast function through association with the RANK/αvβ3 integrin complex. J Cell Physiol (2021)
Kweon HY, Lee MN, Dorfel M, Seo S, Gottlieb L, PaPazyan T, McTiernan N, Ree R, Bolton D, Garcia A, Flory M, Crain J, Sebold A, Lyons S, Ismail A, Marchi E, Sonn SK, Jeong SJ, Jeon S, Ju S, Conway SJ, Kim T, Kim HS, Lee C, Roh TY, Arnesen T, Marmorstein R, Oh GT, Lyon GJ. Naa12 compensates for Naa10 in mice in the amino-terminal acetylation pathway. Elife (2021)
Hyun Jin Kim, Jiae Lee, Gong-Rak Lee, Narae Kim, Hye In Lee, Minjeong Kwon, Nam Young Kim, Jin Ha Park, Ye Hee Kang, Hyeong Ju Song, TaeSoo Kim, Dong Min Shin, Woojin Jeong, Flunarizine inhibits osteoclastogenesis by regulating calcium signaling and promotes osteogenesis, J Cell Physiol (2021)
Hwa-Ryeon Kim, Juhye Yim, Hye-Been Yoo, Seung Eon Lee, Sumin Oh, Sungju Jung, Chang-Il Hwang, Dong-Myung Shin, TaeSoo Kim, Kyung Hyun Yoo, You-Sun Kim, Han-Woong Lee, Jae-Seok Roe, EVI1 activates tumor-promoting transcriptional enhancers in pancreatic cancer, NAR Cancer 3(2):zcab023 (2021)
2020
Ji Hyun Kim†, Chae Young Yoon†, Yukyung Jun†, Bo Bae Lee, Ji Eun Lee, So Dam Ha, Hyeonju Woo, Ahyoung Choi, Sanghyuk Lee, Woojin Jeong, Ji Hyung Kim, TaeSoo Kim*
NuA3 HAT antagonizes the Rpd3S and Rpd3L HDACs to optimize mRNA and lncRNA expression dynamics
Nucleic Acids Research, gkaa781 (2020)
Min kyung Lee, TaeSoo Kim*
Histone H4-Specific Deacetylation at Active Coding Regions by Hda1C
Molecules and Cells, In press (2020)
Taek-Yeol Jung, Jae-Eun Ryu, Mi-Mi Jang, Soh-Yeon Lee, Gyu-Rin Jin, Chan-Woo Kim, Chae-Young Lee, Hyelee Kim, EungHan Kim, Sera Park, Seonjeong Lee, Cheolju Lee, Wankyu Kim, TaeSoo Kim, Soo-Young Lee, Bong-Gun Ju, Hyun-Seok Kim, Naa20, the catalytic subunit of NatB complex, contributes to hepatocellular carcinoma by regulating the LKB1-AMPK-mTOR axis. Exp Mol Med. 52(11):1831-1844 (2020).
2019
So Dam Ha#, Seokjin Ham#, Min Young Kim#, Ji Hyun Kim, Insoon Jang, Bo Bae Lee, Min Kyung Lee, Jin-Taek Hwang, Tae-Young Roh*, TaeSoo Kim*
Transcription-dependent targeting of Hda1C to hyperactive genes mediates H4-specific deacetylation in yeast
Nature Communications, 10, 4270 (2019)
Min Young Kim#, Ji Eun Lee#, Lark Kyun Kim*, TaeSoo Kim*
Epigenetic memory in gene regulation and immune response.
BMB Reports 52, 127-132(2019)
2018
Bo Bae Lee†, Ahyoung Choi†, Ji Hyun Kim, Yukyung Jun, Hyeonju Woo, So Dam Ha, Chae Young Yoon, Jin-Taek Hwang, Lars Steinmetz, Stephen Buratowski, Sanghyuk Lee, Hye Young Kim*, TaeSoo Kim*
Rpd3L HDAC links H3K4me3 to transcriptional repression memory.
Nucleic Acids Research, 46(16):8261-8274 (2018)
2017
Soares LM, He PC, Chun Y, Suh H, Kim T, Buratowski S.
Determinants of Histone H3K4 Methylation Patterns.
Molecular Cell 68(4):773-785 (2017)
Chung CG, Kwon MJ, Jeon KH, Hyeon DY, Han MH, Park JH, Cha IJ, Cho JH, Kim K, Rho S, Kim GR, Jeong H, Lee JW, Kim T, Kim K, Kim KP, Ehlers MD, Hwang D, Lee SB
Golgi Outpost Synthesis Impaired by Toxic Polyglutamine Proteins Contributes to Dendritic Pathology in Neurons
Cell Reports 20, 356-369 (2017)
Lee BB#, Kim JH#, Kim T*
Fine-tuning of gene expression dynamics by the Set2-Rpd3S pathway
BMB Reports 50, 162-163 (2017) # Co-first authors
Hyeonju Woo#, So Dam Ha#, Sung Bae Lee, Stephen Buratowski, TaeSoo Kim*
Modulation of gene expression dynamics by co-transcriptional histone methylations
Experimental & Molecular Medicine e326 (2017) # Co-first authors
Min Jee Kwon, Jeong-Hoon Kim, TaeSoo Kim, Sung Bae Lee
Pharmacological intervention of early neuropathy in neurodegenerative diseases
Pharmacological Research 119, 169-177 (2017)
2016
Ji Hyun Kim#, Bo Bae Lee#, Young Mi Oh, Chenchen Zhu, Lars M. Steinmetz, Yookyeong Lee, Wan Kyu Kim, Sung Bae Lee, Stephen Buratowski*, TaeSoo Kim*
Modulation of mRNA and lncRNA expression dynamics by the Set2-Rpd3S pathway
Nature Communications 7, 13534 (2016)
2014
Hye Young Kim, Sung Bae Lee, Hyen Sam Kang, Goo Taeg Oh, TaeSoo Kim*
Two distinct domains of Flo8 activator mediates its role in transcriptional activation and the physical interaction with Mss11
BBRC 449, 202-207 (2014)
2013
Sung Bae Lee, Hyen Sam Kang, TaeSoo Kim*
Nrg1 functions as a global transcriptional repressor of glucose-repressed genes through its direct binding to the specific promoter regions.
BBRC 439, 501–505 (2013)
2012
TaeSoo Kim, Zhenyu Xu, Sandra Clauder-Münster, Lars M. Steinmetz, Stephen Buratowski
Set3 HDAC mediates the effects of overlapping non-coding transcription on gene induction kinetics
Cell 150, 1158 – 1169 (2012)
Marta Radman-Livaja, Tiffani K. Quan, Lourdes Valenzuela, Jennifer Armstrong, TaeSoo Kim, Stephen Buratowski, Oliver J. Rando, Grant A. Hartzog
A Key Role for Chd1 in Histone H3 Turnover at the 3’ Ends of Long Genes in Yeast
PLOS GENETICS 8, e1002811 (2012)
2011
Timothy W. Sikorski, Scott B. Ficarro, John Holik, TaeSoo Kim, Oliver J. Rando, Jarrod A. Marto, Stephen Buratowski
Sub1 and RPA associate with RNA Polymerase II at different stages of transcription. Molecular Cell 44, 397-409 (2011)
Tineke L. Lenstra, Joris J. Benschop, TaeSoo Kim, Julia M. Schulze, Nathalie A.C.H. Brabers, Thanasis Margaritis, Loes A.L. van de Pasch, Sebastiaan A.A.C. van Heesch, Mariel O. Brok, Marian J.A. Groot Koerkamp, Cheuk Ko, Dik van Leenen, Katrin Sameith, Sander R. van Hooff, Philip Lijnzaad, Patrick Kemmeren, Thomas Hentrich, Michael S. Kobor, Stephen Buratowski, Frank C.P.Holstege.
The specificity and topology of chromatin interaction pathways in yeast. Molecular Cell 42, 536-549 (2011)
Stephen Buratowski and TaeSoo Kim
The Role of Cotranscriptional Histone Methylations. Cold Spring Harb Symp Quant Biol. (2011) Mar 29
2010
TaeSoo Kim, Chih Long Liu, Moran Yassour, John Holik, Nir Friedman, Stephen Buratowski, Oliver J. Rando.
RNA polymerase mapping during stress responses reveals widespread nonproductive transcription in yeast.
Genome Biology 11, R75 (2010)
2009
TaeSoo Kim and Stephen Buratowski
Dimethylation of H3K4 by Set1 recruits the Set3 histone deacetylase complex to 5’ transcribed regions.
Cell 137, 259-272 (2009)
2007
Maite Huarte, Fei Lan, TaeSoo Kim, Matthew W. Vaughn, Mikel Zaratiegui, Robert A. Martienssen, Stephen Buratowski and Yang Shi
The fission yeast JMJ2 reverses histone H3 lysine 4 tri-methylation. J Biol Chem. 282, 14262 - 14271 (2007)
TaeSoo Kim and Stephen Buratowski
Two Saccharomyces cerevisiae JmjC domain proteins demethylate histone H3 K36 in transcribed regions to promote elongation.
J Biol Chem. 282, 20827 - 20835 (2007) - JBC paper of the week -Faculty of 1000 Biology “Must read”
2004
TaeSoo Kim, HyeYoung Kim, JinHo Yoon, and HyenSam Kang.
Recruitment of the Swi/Snf Complex by Ste12-Tec1 Promotes Flo8-Mss11-Mediated Activation of STA1 Expression.
Mol. Cell. Biol. 21, 9542–9556 (2004)
TaeSoo Kim, SungBae Lee, and HyenSam Kang
Glucose repression of STA1 expression is mediated by the Nrg1 and Sfl1 repressors and the Srb8-11 complex.
Mol. Cell. Biol. 17, 7695-7706 (2004)
2003
TaeSoo Kim, JiYoen Ahn, JinHo Yoon, and HyenSam Kang
STA10 repression of STA gene expression is caused by a defective activator, flo8, in Saccharomyces cerevisiae.
Curr .Genet. 44, 261-267 (2003)